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Selection of a novel DNA aptamer against OFA/iLRP for targeted delivery of doxorubicin to AML cells

The standard treatment for most acute myeloid leukemia (AML) is chemotherapy, which is often associated with severe adverse effects. One strategy to reduce the adverse effects is targeted therapy that can selectively deliver anticancer drugs to tumor cells. Immature laminin receptor protein (OFA/iLR...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: An, Yacong, Hu, Yan, Li, Xundou, Li, Zhaoyi, Duan, Jinhong, Yang, Xian-Da
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517398/
https://ncbi.nlm.nih.gov/pubmed/31089250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43910-3
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