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Development of a live attenuated bivalent oral vaccine against Shigella sonnei shigellosis and typhoid fever
Shigella sonnei (Ss) and Salmonella Typhi cause significant morbidity and mortality. We exploited the safety record of the oral, attenuated S. Typhi vaccine (Ty21a) by utilizing it as a vector to develop a bivalent oral vaccine to protect against Ss shigellosis and typhoid fever. We recombineered th...
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| Publicado no: | J Infect Dis |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6516681/ https://ncbi.nlm.nih.gov/pubmed/27803169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw528 |
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