Incidence, features, and prognosis of immune-related adverse events involving the thyroid gland induced by nivolumab

BACKGROUND: Blocking the PD-1 pathway induces immune-related adverse events (irAEs) which often involve the thyroid gland (thyroid irAEs). Clinical features of a thyroid irAE including its predictability and relationship to prognosis remain to be elucidated. METHODS: Two hundred consecutive patients...

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Αποθηκεύτηκε σε:
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Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Yamauchi, Ichiro, Yasoda, Akihiro, Matsumoto, Shigemi, Sakamori, Yuichi, Kim, Young Hak, Nomura, Motoo, Otsuka, Atsushi, Yamasaki, Toshinari, Saito, Ryoichi, Kitamura, Morimasa, Kitawaki, Toshio, Hishizawa, Masakatsu, Kawaguchi-Sakita, Nobuko, Fujii, Toshihito, Taura, Daisuke, Sone, Masakatsu, Inagaki, Nobuya
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2019
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516638/
https://ncbi.nlm.nih.gov/pubmed/31086392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216954
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