Upfront Surgical Resection of Melanoma Brain Metastases Provides a Bridge Toward Immunotherapy‐Mediated Systemic Control

BACKGROUND. Immune checkpoint blockade has systemic efficacy in patients with metastatic melanoma, including those with brain metastases (MBMs). However, immunotherapy‐induced intracranial tumoral inflammation can lead to neurologic compromise, requiring steroids, which abrogate the systemic efficac...

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Dades bibliogràfiques
Publicat a:Oncologist
Autors principals: Alvarez‐Breckenridge, Christopher, Giobbie‐Hurder, Anita, Gill, Corey M., Bertalan, Mia, Stocking, Jackson, Kaplan, Alexander, Nayyar, Naema, Lawrence, Donald P., Flaherty, Keith T., Shih, Helen A., Oh, Kevin, Batchelor, Tracy T., Cahill, Daniel P., Sullivan, Ryan, Brastianos, Priscilla K.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2019
Matèries:
Neuro‐Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516108/
https://ncbi.nlm.nih.gov/pubmed/30796152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0306
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