Upfront Surgical Resection of Melanoma Brain Metastases Provides a Bridge Toward Immunotherapy‐Mediated Systemic Control

BACKGROUND. Immune checkpoint blockade has systemic efficacy in patients with metastatic melanoma, including those with brain metastases (MBMs). However, immunotherapy‐induced intracranial tumoral inflammation can lead to neurologic compromise, requiring steroids, which abrogate the systemic efficac...

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Bibliografiske detaljer
Udgivet i:Oncologist
Main Authors: Alvarez‐Breckenridge, Christopher, Giobbie‐Hurder, Anita, Gill, Corey M., Bertalan, Mia, Stocking, Jackson, Kaplan, Alexander, Nayyar, Naema, Lawrence, Donald P., Flaherty, Keith T., Shih, Helen A., Oh, Kevin, Batchelor, Tracy T., Cahill, Daniel P., Sullivan, Ryan, Brastianos, Priscilla K.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2019
Fag:
Neuro‐Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516108/
https://ncbi.nlm.nih.gov/pubmed/30796152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0306
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