Upfront Surgical Resection of Melanoma Brain Metastases Provides a Bridge Toward Immunotherapy‐Mediated Systemic Control

BACKGROUND. Immune checkpoint blockade has systemic efficacy in patients with metastatic melanoma, including those with brain metastases (MBMs). However, immunotherapy‐induced intracranial tumoral inflammation can lead to neurologic compromise, requiring steroids, which abrogate the systemic efficac...

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Détails bibliographiques
Publié dans:Oncologist
Auteurs principaux: Alvarez‐Breckenridge, Christopher, Giobbie‐Hurder, Anita, Gill, Corey M., Bertalan, Mia, Stocking, Jackson, Kaplan, Alexander, Nayyar, Naema, Lawrence, Donald P., Flaherty, Keith T., Shih, Helen A., Oh, Kevin, Batchelor, Tracy T., Cahill, Daniel P., Sullivan, Ryan, Brastianos, Priscilla K.
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Inc. 2019
Sujets:
Neuro‐Oncology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516108/
https://ncbi.nlm.nih.gov/pubmed/30796152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0306
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