Upfront Surgical Resection of Melanoma Brain Metastases Provides a Bridge Toward Immunotherapy‐Mediated Systemic Control

BACKGROUND. Immune checkpoint blockade has systemic efficacy in patients with metastatic melanoma, including those with brain metastases (MBMs). However, immunotherapy‐induced intracranial tumoral inflammation can lead to neurologic compromise, requiring steroids, which abrogate the systemic efficac...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Alvarez‐Breckenridge, Christopher, Giobbie‐Hurder, Anita, Gill, Corey M., Bertalan, Mia, Stocking, Jackson, Kaplan, Alexander, Nayyar, Naema, Lawrence, Donald P., Flaherty, Keith T., Shih, Helen A., Oh, Kevin, Batchelor, Tracy T., Cahill, Daniel P., Sullivan, Ryan, Brastianos, Priscilla K.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Neuro‐Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516108/
https://ncbi.nlm.nih.gov/pubmed/30796152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0306
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