Upfront Surgical Resection of Melanoma Brain Metastases Provides a Bridge Toward Immunotherapy‐Mediated Systemic Control

BACKGROUND. Immune checkpoint blockade has systemic efficacy in patients with metastatic melanoma, including those with brain metastases (MBMs). However, immunotherapy‐induced intracranial tumoral inflammation can lead to neurologic compromise, requiring steroids, which abrogate the systemic efficac...

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Detalles Bibliográficos
Publicado en:Oncologist
Main Authors: Alvarez‐Breckenridge, Christopher, Giobbie‐Hurder, Anita, Gill, Corey M., Bertalan, Mia, Stocking, Jackson, Kaplan, Alexander, Nayyar, Naema, Lawrence, Donald P., Flaherty, Keith T., Shih, Helen A., Oh, Kevin, Batchelor, Tracy T., Cahill, Daniel P., Sullivan, Ryan, Brastianos, Priscilla K.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Inc. 2019
Assuntos:
Neuro‐Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516108/
https://ncbi.nlm.nih.gov/pubmed/30796152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0306
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