Correlating Cystic Fibrosis Transmembrane Conductance Regulator Function with Clinical Features to Inform Precision Treatment of Cystic Fibrosis

Rationale: The advent of precision treatment for cystic fibrosis using small-molecule therapeutics has created a need to estimate potential clinical improvements attributable to increases in cystic fibrosis transmembrane conductance regulator (CFTR) function. Objectives: To derive CFTR function of a...

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Pubblicato in:Am J Respir Crit Care Med
Autori principali: McCague, Allison F., Raraigh, Karen S., Pellicore, Matthew J., Davis-Marcisak, Emily F., Evans, Taylor A., Han, Sangwoo T., Lu, Zhongzhou, Joynt, Anya T., Sharma, Neeraj, Castellani, Carlo, Collaco, Joseph M., Corey, Mary, Lewis, Michelle H., Penland, Chris M., Rommens, Johanna M., Stephenson, Anne L., Sosnay, Patrick R., Cutting, Garry R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2019
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515867/
https://ncbi.nlm.nih.gov/pubmed/30888834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201901-0145OC
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