Correlating Cystic Fibrosis Transmembrane Conductance Regulator Function with Clinical Features to Inform Precision Treatment of Cystic Fibrosis

Rationale: The advent of precision treatment for cystic fibrosis using small-molecule therapeutics has created a need to estimate potential clinical improvements attributable to increases in cystic fibrosis transmembrane conductance regulator (CFTR) function. Objectives: To derive CFTR function of a...

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Vydáno v:Am J Respir Crit Care Med
Hlavní autoři: McCague, Allison F., Raraigh, Karen S., Pellicore, Matthew J., Davis-Marcisak, Emily F., Evans, Taylor A., Han, Sangwoo T., Lu, Zhongzhou, Joynt, Anya T., Sharma, Neeraj, Castellani, Carlo, Collaco, Joseph M., Corey, Mary, Lewis, Michelle H., Penland, Chris M., Rommens, Johanna M., Stephenson, Anne L., Sosnay, Patrick R., Cutting, Garry R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515867/
https://ncbi.nlm.nih.gov/pubmed/30888834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201901-0145OC
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