Negative regulation of glial Tim‐3 inhibits the secretion of inflammatory factors and modulates microglia to antiinflammatory phenotype after experimental intracerebral hemorrhage in rats

AIMS: To investigate the critical role of Tim‐3 in the polarization of microglia in intracerebral hemorrhage (ICH)‐induced secondary brain injury (SBI). METHODS: An in vivo ICH model was established by autologous whole blood injection into the right basal ganglia in rats. The primary cultured microg...

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Udgivet i:CNS Neurosci Ther
Main Authors: Chen, Zhou‐Qing, Yu, Hao, Li, Hai‐Ying, Shen, Hai‐Tao, Li, Xiang, Zhang, Ju‐Yi, Zhang, Zhu‐Wei, Wang, Zhong, Chen, Gang
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515709/
https://ncbi.nlm.nih.gov/pubmed/30677253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13100
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