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PTPRK Expression Is Downregulated in Drug Resistant Ovarian Cancer Cell Lines, and Especially in ALDH1A1 Positive CSCs-Like Populations

Background: Ovarian cancer is the 7th most common cancer and 8th most mortal cancer among woman. The standard treatment includes cytoreduction surgery followed by chemotherapy. Unfortunately, in most cases, after treatment, cancer develops drug resistance. Decreased expression and/or activity of pro...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Świerczewska, Monika, Sterzyńska, Karolina, Wojtowicz, Karolina, Kaźmierczak, Dominika, Iżycki, Dariusz, Nowicki, Michał, Zabel, Maciej, Januchowski, Radosław
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515253/
https://ncbi.nlm.nih.gov/pubmed/31027318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20082053
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