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Improvement of l-Leucine Production in Corynebacterium glutamicum by Altering the Redox Flux

The production of l-leucine was improved by the disruption of ltbR encoding transcriptional regulator and overexpression of the key genes (leuAilvBNCE) of the l-leucine biosynthesis pathway in Corynebacterium glutamicum XQ-9. In order to improve l-leucine production, we rationally engineered C. glut...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Wang, Ying-Yu, Zhang, Feng, Xu, Jian-Zhong, Zhang, Wei-Guo, Chen, Xiu-Lai, Liu, Li-Ming
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515235/
https://ncbi.nlm.nih.gov/pubmed/31022947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20082020
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