Characterization of abscopal effects of intratumoral electroporation-mediated IL-12 gene therapy

Intratumoral electroporation-mediated IL-12 gene therapy (IT-pIL12/EP) has been shown to be safe and effective in clinical trials, demonstrating systemic antitumor effects with local delivery of this potent cytokine. We recently optimized our IL-12 gene delivery platform to increase transgene expres...

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Detalhes bibliográficos
Publicado no:Gene Ther
Main Authors: Mukhopadhyay, Anandaroop, Wright, Jocelyn, Shirley, Shawna, Canton, David A., Burkart, Christoph, Connolly, Richard J., Campbell, Jean S., Pierce, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514882/
https://ncbi.nlm.nih.gov/pubmed/30323352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41434-018-0044-5
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