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CAR-T with License to Kill Solid Tumors in Search of a Winning Strategy
Artificial receptors designed for adoptive immune therapies need to absolve dual functions: antigen recognition and abilities to trigger the lytic machinery of reprogrammed effector T lymphocytes. In this way, CAR-T cells deliver their cytotoxic hit to cancer cells expressing targeted tumor antigens...
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| Gepubliceerd in: | Int J Mol Sci |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
MDPI
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6514830/ https://ncbi.nlm.nih.gov/pubmed/30999624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081903 |
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