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Tri-Cyclic Nucleobase Analogs and Their Ribosides as Substrates of Purine-Nucleoside Phosphorylases. II Guanine and Isoguanine Derivatives

Etheno-derivatives of guanine, O(6)-methylguanine, and isoguanine were prepared and purified using standard methods. The title compounds were examined as potential substrates of purine-nucleoside phosphorylases from various sources in the reverse (synthetic) pathway. It was found that 1,N(2)-etheno-...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Stachelska-Wierzchowska, Alicja, Wierzchowski, Jacek, Górka, Michał, Bzowska, Agnieszka, Wielgus-Kutrowska, Beata
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514686/
https://ncbi.nlm.nih.gov/pubmed/30995785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24081493
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