PBRM1 Regulates Stress Response in Epithelial Cells

Polybromo1 (PBRM1) is a chromatin remodeler subunit highly mutated in cancer, particularly clear cell renal carcinoma. PBRM1 is a member of the SWI/SNF subcomplex, PBAF (PBRM1-Brg1/Brm-associated factors), and is characterized by six tandem bromodomains. Here we establish a role for PBRM1 in epithel...

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Publicat a:iScience
Autors principals: Porter, Elizabeth G., Dhiman, Alisha, Chowdhury, Basudev, Carter, Benjamin C., Lin, Hang, Stewart, Jane C., Kazemian, Majid, Wendt, Michael K., Dykhuizen, Emily C.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514269/
https://ncbi.nlm.nih.gov/pubmed/31077944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.04.027
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