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Spermidine Synthase (SPDS) Undergoes Concerted Structural Rearrangements Upon Ligand Binding – A Case Study of the Two SPDS Isoforms From Arabidopsis thaliana

Spermidine synthases (SPDSs) catalyze the production of the linear triamine, spermidine, from putrescine. They utilize decarboxylated S-adenosylmethionine (dc-SAM), a universal cofactor of aminopropyltransferases, as a donor of the aminopropyl moiety. In this work, we describe crystal structures of...

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Detalhes bibliográficos
Publicado no:Front Plant Sci
Main Authors: Sekula, Bartosz, Dauter, Zbigniew
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514230/
https://ncbi.nlm.nih.gov/pubmed/31134111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2019.00555
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