20(S)-Protopanaxadiol Inhibits Angiotensin II-Induced Epithelial- Mesenchymal Transition by Downregulating SIRT1

20(S)-Protopanaxadiol (PPD) is one of the major active metabolites in ginseng saponin. Our previous studies revealed a broad spectrum of antitumor effects of PPD. Angiotensin II (Ang II), the biologically active peptide of the renin-angiotensin system (RAS), plays a critical role in the metastasis o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Pharmacol
Prif Awduron: Wang, Yuchen, Xu, Huali, Fu, Wenwen, Lu, Zeyuan, Guo, Minyu, Wu, Xueji, Sun, Mingyang, Liu, Yanzhe, Yu, Xiaofeng, Sui, Dayun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2019
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514190/
https://ncbi.nlm.nih.gov/pubmed/31133857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00475
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