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Cholesterol and Cardiolipin Importance in Local Anesthetics–Membrane Interactions: The Langmuir Monolayer Study

Local anesthetics (LAs) are known to act on membrane level; however, the molecular mechanism of their activity is still not fully understood. One hypothesis holds that these drugs can incorporate into lipid membrane of nerve cells and in this way change conformation of channel proteins responsible f...

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Detalhes bibliográficos
Publicado no:J Membr Biol
Main Authors: Mildner, Justyna, Wnętrzak, Anita, Dynarowicz-Latka, Patrycja
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514108/
https://ncbi.nlm.nih.gov/pubmed/30506104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-018-0055-6
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