Mitochondrial Dysfunction Is Inducible in Lymphoblastoid Cell Lines From Children With Autism and May Involve the TORC1 Pathway

We previously developed a lymphoblastoid cell line (LCL) model of mitochondrial dysfunction in autism spectrum disorder (ASD); some individuals with ASD showed mitochondrial dysfunction (AD-A) while other individuals (AD-N) demonstrated mitochondrial respiration similar to controls (CNT). To test th...

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Bibliographic Details
Published in:Front Psychiatry
Main Authors: Bennuri, Sirish C., Rose, Shannon, Frye, Richard E.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Psychiatry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514096/
https://ncbi.nlm.nih.gov/pubmed/31133888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2019.00269
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