Decreased Glycogenolysis by miR-338-3p Promotes Regional Glycogen Accumulation Within the Spinal Cord of Amyotrophic Lateral Sclerosis Mice

Metabolic dysfunction is a hallmark of age-related neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). But the crosstalk between metabolic alteration and disease progression in ALS is still largely unknown. Glycogen, a branched polymer of glucose residues, is universally recog...

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Bibliographic Details
Published in:Front Mol Neurosci
Main Authors: Li, Chunyu, Wei, Qianqian, Gu, Xiaojing, Chen, Yongping, Chen, Xueping, Cao, Bei, Ou, Ruwei, Shang, Huifang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514045/
https://ncbi.nlm.nih.gov/pubmed/31133799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00114
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