Synthesis and Statistical Optimization of Poly (Lactic-Co-Glycolic Acid) Nanoparticles Encapsulating GLP1 Analog Designed for Oral Delivery

PURPOSE: To design and stabilize Liraglutide loaded poly (lactic-co-glycolic acid) nanoparticles (PLGA NPs) proper for oral administration. METHODS: PLGA NPs were prepared by means of double emulsion solvent evaporation method and optimized by applying 7-factor 2-level Plackett-Burman screening desi...

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Vydáno v:Pharm Res
Hlavní autoři: Ismail, Ruba, Sovány, Tamás, Gácsi, Attila, Ambrus, Rita, Katona, Gábor, Imre, Norbert, Csóka, Ildikó
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2019
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513835/
https://ncbi.nlm.nih.gov/pubmed/31087188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-019-2620-9
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