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The activity of the saponin ginsenoside Rh2 is enhanced by the interaction with membrane sphingomyelin but depressed by cholesterol

The membrane activity of some saponins, such as digitonin or alpha-hederin, is usually attributed to their interaction with membrane cholesterol (Chol). This contrasts with our recent publication showing that Chol, contrary to sphingomyelin (SM), can delay the cytotoxicity of the saponin ginsenoside...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Verstraeten, Sandrine L., Deleu, Magali, Janikowska-Sagan, Maria, Claereboudt, Emily J. S., Lins, Laurence, Tyteca, Donatienne, Mingeot-Leclercq, Marie-Paule
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513819/
https://ncbi.nlm.nih.gov/pubmed/31086211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43674-w
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