Impact of pre-analytical differences on biomarkers in the ADNI and PPMI studies: implications in the era of classifying disease based on biomarkers

BACKGROUND: Neurodegenerative diseases require characterization based on underlying biology using biochemical biomarkers. Mixed pathology complicates discovery of biomarkers and characterization of cohorts, but inclusion of greater numbers of patients with different, related diseases with frequently...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Stewart, Tessandra, Shi, Min, Mehrotra, Aanchal, Aro, Patrick, Soltys, David, Kerr, Kathleen F., Zabetian, Cyrus P., Peskind, Elaine R., Taylor, Peggy, Shaw, Leslie M., Trojanowski, John Q., Zhang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513710/
https://ncbi.nlm.nih.gov/pubmed/30958379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190069
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