Stevioside inhibits experimental fibrosis by downregulating profibrotic Smad pathways and blocking HSC activation

Liver cirrhosis is associated with increased morbidity and mortality with important health and social consequences; however, an effective treatment has not been found yet. Previous reports have shown some beneficial effects of stevioside (SVT) in different diseases, but the ability of SVT to inhibit...

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Gepubliceerd in:Basic Clin Pharmacol Toxicol
Hoofdauteurs: Casas-Grajales, Sael, Alvarez-Suarez, Diana, Ramos-Tovar, Erika, Buendía-Montaño, Laura Dayana, Reyes-Gordillo, Karina, Camacho, Javier, Tsutsumi, Víctor, Lakshman, M. Raj, Muriel, Pablo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513700/
https://ncbi.nlm.nih.gov/pubmed/30561898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcpt.13194
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