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Chemical-PDMS Binding Kinetics and Implications for Bioavailability in Microfluidic Devices

Microfluidic organ-on-chip devices constructed from polydimethysiloxane (PDMS) have proven useful in studying both beneficial and adverse effects of drugs, supplements, and potential toxicants. Despite multiple advantages, one clear drawback of PDMS-based devices is binding of hydrophobic chemicals...

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Detalhes bibliográficos
Publicado no:Lab Chip
Main Authors: Auner, Alexander W., Tasneem, Kazi M., Markov, Dmitry A., McCawley, Lisa J., Hutson, M. Shane
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512955/
https://ncbi.nlm.nih.gov/pubmed/30720811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8lc00796a
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