Development and Validation of a Prostate Cancer Genomic Signature that Predicts Early ADT Treatment Response Following Radical Prostatectomy

PURPOSE: Currently, no genomic signature exists to distinguish men most likely to progress on adjuvant androgen deprivation therapy (ADT) after radical prostatectomy for high-risk prostate cancer. Here we develop and validate a gene expression signature to predict response to postoperative ADT. EXPE...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Karnes, R. Jeffrey, Sharma, Vidit, Choeurng, Voleak, Ashab, Hussam Al-Deen, Erho, Nicholas, Alshalalfa, Mohammed, Trock, Bruce, Ross, Ashley, Yousefi, Kasra, Tsai, Harrison, Zhao, Shuang G., Tosoian, Jeffrey J., Haddad, Zaid, Takhar, Mandeep, Chang, S. Laura, Spratt, Daniel E., Abdollah, Firas, Jenkins, Robert B., Klein, Eric A., Nguyen, Paul L., Dicker, Adam P., Den, Robert B., Davicioni, Elai, Feng, Felix Y., Lotan, Tamara L., Schaeffer, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512950/
https://ncbi.nlm.nih.gov/pubmed/29760221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2745
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