A general platform for antibody purification utilizing engineered-micelles

We introduce a new concept and potentially general platform for antibody (Ab) purification that does not rely on chromatography or specific ligands (e.g., Protein A); rather, it makes use of detergent aggregates capable of efficiently capturing Ab while rejecting hydrophilic impurities. Captured Ab...

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Veröffentlicht in:MAbs
Hauptverfasser: Dhandapani, Gunasekaran, Howard, Assaf, Truong, Thien Van, Baiju, Thekke V., Kesselman, Ellina, Friedman, Noga, Wachtel, Ellen, Sheves, Mordechai, Danino, Dganit, Namboothiri, Irishi N. N., Patchornik, Guy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
Schlagworte:
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512930/
https://ncbi.nlm.nih.gov/pubmed/30618334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1565749
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