Prediagnostic plasma metabolomics and the risk of amyotrophic lateral sclerosis

OBJECTIVE: To identify prediagnostic plasma metabolomic biomarkers associated with amyotrophic lateral sclerosis (ALS). METHODS: We conducted a global metabolomic study using a nested case-control study design within 5 prospective cohorts and identified 275 individuals who developed ALS during follo...

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Bibliografske podrobnosti
izdano v:Neurology
Main Authors: Bjornevik, Kjetil, Zhang, Zhongli, O'Reilly, Éilis J., Berry, James D., Clish, Clary B., Deik, Amy, Jeanfavre, Sarah, Kato, Ikuko, Kelly, Rachel S., Kolonel, Laurence N., Liang, Liming, Marchand, Loic Le, McCullough, Marjorie L., Paganoni, Sabrina, Pierce, Kerry A., Schwarzschild, Michael A., Shadyab, Aladdin H., Wactawski-Wende, Jean, Wang, Dong D., Wang, Ying, Manson, JoAnn E., Ascherio, Alberto
Format: Artigo
Jezik:Inglês
Izdano: Lippincott Williams & Wilkins 2019
Teme:
Null Hypothesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512888/
https://ncbi.nlm.nih.gov/pubmed/30926684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000007401
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