Prediagnostic plasma metabolomics and the risk of amyotrophic lateral sclerosis

OBJECTIVE: To identify prediagnostic plasma metabolomic biomarkers associated with amyotrophic lateral sclerosis (ALS). METHODS: We conducted a global metabolomic study using a nested case-control study design within 5 prospective cohorts and identified 275 individuals who developed ALS during follo...

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Bibliografiska uppgifter
I publikationen:Neurology
Huvudupphovsmän: Bjornevik, Kjetil, Zhang, Zhongli, O'Reilly, Éilis J., Berry, James D., Clish, Clary B., Deik, Amy, Jeanfavre, Sarah, Kato, Ikuko, Kelly, Rachel S., Kolonel, Laurence N., Liang, Liming, Marchand, Loic Le, McCullough, Marjorie L., Paganoni, Sabrina, Pierce, Kerry A., Schwarzschild, Michael A., Shadyab, Aladdin H., Wactawski-Wende, Jean, Wang, Dong D., Wang, Ying, Manson, JoAnn E., Ascherio, Alberto
Materialtyp: Artigo
Språk:Inglês
Publicerad: Lippincott Williams & Wilkins 2019
Ämnen:
Null Hypothesis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512888/
https://ncbi.nlm.nih.gov/pubmed/30926684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000007401
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