Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome

Cytokine release syndrome (CRS) is a life-threatening complication of several new immunotherapies used to treat cancers and autoimmune diseases(1–5). Here we report that atrial natriuretic peptide can protect mice from CRS induced by such agents by reducing the levels of circulating catecholamines....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nature
Egile Nagusiak: Staedtke, Verena, Bai, Ren-Yuan, Kim, Kibem, Darvas, Martin, Davila, Marco L., Riggins, Gregory J., Rothman, Paul B., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512810/
https://ncbi.nlm.nih.gov/pubmed/30542164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0774-y
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