Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome

Cytokine release syndrome (CRS) is a life-threatening complication of several new immunotherapies used to treat cancers and autoimmune diseases(1–5). Here we report that atrial natriuretic peptide can protect mice from CRS induced by such agents by reducing the levels of circulating catecholamines....

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Staedtke, Verena, Bai, Ren-Yuan, Kim, Kibem, Darvas, Martin, Davila, Marco L., Riggins, Gregory J., Rothman, Paul B., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512810/
https://ncbi.nlm.nih.gov/pubmed/30542164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0774-y
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