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A55 CELL-MEDIATED DELIVERY OF GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR (GDNF) IS NEUROPROTECTIVE FOR MYENTERIC NEURONS

BACKGROUND: Transmural inflammation of the intestine causes structural and functional damage to the enteric nervous system (ENS), that contributes to dysmotility. Elsewhere, neurotrophins can promote neuronal survival and recovery from damage, but a similar role for GDNF, the principal neurotrophin...

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Bibliographic Details
Published in:J Can Assoc Gastroenterol
Main Authors: Zoumboulakis, D P, Lourenssen, S, Blennerhassett, M G
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512691/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz006.054
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