A50 MICROBIOTA-MAST CELL INTERACTIONS IN A HUMANIZED MOUSE MODEL OF IBS

BACKGROUND: Accumulating evidence suggests that mast cells play an important role in the pathogenesis of Irritable Bowel Syndrome (IBS). Colonic mast cells are increased in patients with IBS, and their products, including histamine and tryptase are putative mediators of visceral hypersensitivity in...

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Detalhes bibliográficos
Publicado no:J Can Assoc Gastroenterol
Main Authors: Shimbori, C, De Palma, G, Lu, J, Verdu, E, Collins, S M, Reed, D E, Vanner, S, Bercik, P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512438/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz006.049
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