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A70 PROTEASE-ACTIVATED RECEPTOR 2 DRIVES COLONIC EPITHELIAL WOUND HEALING VIA EGFR TRANSACTIVATION

BACKGROUND: Compromised intestinal barrier function is a prominent feature of inflammatory bowel diseases. Epithelial restitution is required in the resolution of inflammation. For this to occur epithelial cells need to transition to migratory phenotype from its normal barrier phenotype. The inflamm...

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Foilsithe in:J Can Assoc Gastroenterol
Main Authors: Bandara, M N, MacNaughton, W
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512432/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz006.069
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