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Mechanistic Target of Rapamycin Complex 1 Signaling Modulates Vascular Endothelial Function Through Reactive Oxygen Species

BACKGROUND: The mechanistic target of rapamycin complex 1 (mTORC1) is an important intracellular energy sensor that regulates gene expression and protein synthesis through its downstream signaling components, the S6‐kinase and the ribosomal S6 protein. Recently, signaling arising from mTORC1 has bee...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Reho, John J., Guo, Deng‐Fu, Rahmouni, Kamal
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512105/
https://ncbi.nlm.nih.gov/pubmed/31020916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.010662
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