Cyclophilin A Protects Cardiomyocytes against Hypoxia/Reoxygenation-Induced Apoptosis via the AKT/Nox2 Pathway

Hypoxia/reoxygenation (H/R) accelerates the process of cardiomyocyte apoptosis during ischemia-reperfusion. Excessive reactive oxygen species (ROS) are a critical driver of oxidative stress injury. Cyclophilin A (CyPA) is a major ROS-induced factor in atherosclerosis. There is a positive feedback me...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Cheng, Fuyu, Yuan, Wei, Cao, Mengfei, Chen, Rui, Wu, Xiuli, Yan, Jinchuan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512079/
https://ncbi.nlm.nih.gov/pubmed/31182989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2717986
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