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A single-input binary counting module based on serine integrase site-specific recombination

A device that counts and records the number of events experienced by an individual cell could have many uses in experimental biology and biotechnology. Here, we report a DNA-based ‘latch’ that switches between two states upon each exposure to a repeated stimulus. The key component of the latch is a...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zhao, Jia, Pokhilko, Alexandra, Ebenhöh, Oliver, Rosser, Susan J, Colloms, Sean D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511857/
https://ncbi.nlm.nih.gov/pubmed/30957849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz245
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