Evaluation of Immune Response against Leishmaniasis in BALB/c Mice Immunized with Cationic DOTAP/DOPE/CHOL Liposomes Containing Soluble Leishmania major Antigens

BACKGROUND: Whole killed Leishmania vaccine reached phase III clinical trials but failed to display significant efficacy in human mainly due to limited Th1 inducer adjuvant. Liposomes consisting of 1, 2-dioleoyl-3trimethylammonium-propane (DOTAP) bearing an inherent adjuvanticity and 1, 2-dioleoyl-L...

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Bibliografiske detaljer
Udgivet i:Iran J Parasitol
Main Authors: HOJATIZADE, Mansure, BADIEE, Ali, KHAMESIPOUR, Ali, JAAFARI, Mahmoud Reza
Format: Artigo
Sprog:Inglês
Udgivet: Tehran University of Medical Sciences 2019
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511587/
https://ncbi.nlm.nih.gov/pubmed/31123470
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