Polymorphisms in microRNA let-7 binding sites of the HIF1AN and CLDN12 genes can predict pathologic complete response to taxane- and platinum-based neoadjuvant chemotherapy in breast cancer

BACKGROUND: Germline genetic polymorphisms in certain genes are associated with response to anthracycline- and taxane-based neoadjuvant chemotherapy in breast cancer (BC). Recent evidence has indicated that microRNA (miRNA) let-7 expression is associated with response to chemotherapeutics. This stud...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Du, Yueyao, Zhou, Liheng, Lin, Yanping, Yin, Kai, Yin, Wenjin, Lu, Jinsong
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511555/
https://ncbi.nlm.nih.gov/pubmed/31157259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.04.26
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