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Conversion of staphylococcal pathogenicity islands to CRISPR-Cas9-based antibacterial drones that cure staph infections in mice

Staphylococcus aureus and other staphylococci continue to cause life-threatening infections in both hospital and community settings. They have become increasingly resistant to antibiotics, especially β-lactams and aminoglycosides, and their infections are now, in many cases, untreatable. Here, we pr...

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Bibliografiska uppgifter
I publikationen:Nat Biotechnol
Huvudupphovsmän: Ram, Geeta, Ross, Hope F., Novick, Richard P., Rodriguez-Pagan, Ivelisse, Jiang, Dunrong
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511514/
https://ncbi.nlm.nih.gov/pubmed/30247487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4203
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