Apolipoprotein A5 alleviates LPS/d-GalN-induced fulminant liver failure in mice by inhibiting TLR4-mediated NF-κB pathway

BACKGROUND: Fulminant liver failure (FHF) is a serious clinical problem and liver transplantation is the major intervention. But the overall survival rate of FHF is low owing to the donated organ shortage. Apolipoprotein A-V (ApoA5) is a regulator of triglyceride metabolism and has been reported to...

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Bibliografiska uppgifter
I publikationen:J Transl Med
Huvudupphovsmän: Tao, Ya-Chao, Wang, Meng-Lan, Wu, Dong-Bo, Luo, Chen, Tang, Hong, Chen, En-Qiang
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2019
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511152/
https://ncbi.nlm.nih.gov/pubmed/31077206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1900-9
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