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Polymorphisms of ADME-related genes and their implications for drug safety and efficacy in Amazonian Amerindians

The variation in the allelic frequencies of polymorphic pharmacogenes among different ethnic groups may be responsible for severe adverse reactions to or altered efficacy of a wide variety of drugs. Amazonian Amerindian populations have a unique genetic profile that may have a fundamental on the eff...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Rodrigues, Juliana Carla Gomes, Fernandes, Marianne Rodrigues, Guerreiro, João Farias, da Silva, Artur Luiz da Costa, Ribeiro-dos-Santos, Ândrea, Santos, Sidney, Santos, Ney Pereira Carneiro dos
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510895/
https://ncbi.nlm.nih.gov/pubmed/31076604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43610-y
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