Apoptotic endothelial cells release small extracellular vesicles loaded with immunostimulatory viral-like RNAs

Endothelial cells have multifaceted interactions with the immune system, both as initiators and targets of immune responses. In vivo, apoptotic endothelial cells release two types of extracellular vesicles upon caspase-3 activation: apoptotic bodies and exosome-like nanovesicles (ApoExos). Only ApoE...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hardy, Marie-Pierre, Audemard, Éric, Migneault, Francis, Feghaly, Albert, Brochu, Sylvie, Gendron, Patrick, Boilard, Éric, Major, François, Dieudé, Mélanie, Hébert, Marie-Josée, Perreault, Claude
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510763/
https://ncbi.nlm.nih.gov/pubmed/31076589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43591-y
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