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Progressive recruitment of mesenchymal progenitors reveals a time-dependent process of cell fate acquisition in mouse and human nephrogenesis

Mammalian nephrons arise from a limited nephron progenitor pool through a reiterative inductive process extending over days (mouse) or weeks (human) of kidney development. Here, we present evidence that human nephron patterning reflects a time-dependent process of recruitment of mesenchymal progenit...

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Pubblicato in:Dev Cell
Autori principali: Lindström, Nils O., De Sena Brandine, Guilherme, Tran, Tracy, Ransick, Andrew, Suh, Gio, Guo, Jinjin, Kim, Albert D., Parvez, Riana K., Ruffins, Seth W., Rutledge, Elisabeth A., Thornton, Matthew E., Grubbs, Brendan, McMahon, Jill A., Smith, Andrew D., McMahon, Andrew P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510587/
https://ncbi.nlm.nih.gov/pubmed/29870722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.05.010
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