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Differences across cyclophilin A orthologs contribute to the host range restriction of hepatitis C virus

The restricted host tropism of hepatitis C virus (HCV) remains incompletely understood, especially post-entry, and has hindered developing an immunocompetent, small animal model. HCV replication in non-permissive species may be limited by incompatibilities between the viral replication machinery and...

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Udgivet i:eLife
Main Authors: Gaska, Jenna M, Balev, Metodi, Ding, Qiang, Heller, Brigitte, Ploss, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510530/
https://ncbi.nlm.nih.gov/pubmed/31074414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44436
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