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Modulating Glucose Metabolism and Lactate Synthesis in Injured Mouse Tendons: Treatment with Dichloroacetate, A Lactate Synthesis Inhibitor, Improves Tendon Healing.

BACKGROUND: Tendon injuries are common problems among athletes. Complete recovery of the mechanical structure and function of ruptured tendons is challenging. It has been demonstrated that upregulation of glycolysis and lactate production occurs in wounds, inflammation sites, and cancerous tumors, a...

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Detalhes bibliográficos
Publicado no:Am J Sports Med
Main Authors: Zhang, K, Hast, MW, Izumi, S, Usami, Y, Shetye, S, Akabudike, N, Philp, NJ, Iwamoto, M, Nissim, I, Soslowsky, LJ, Enomoto-Iwamoto, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510478/
https://ncbi.nlm.nih.gov/pubmed/29927623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0363546518778789
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