Malaria in pregnancy alters L-arginine bioavailability and placental vascular development

Reducing adverse birth outcomes due to malaria in pregnancy (MIP) is a global health priority. However, there are few safe and effective interventions. L-arginine is an essential amino acid in pregnancy and an immediate precursor in the biosynthesis of nitric oxide (NO), but there are limited data o...

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Udgivet i:Sci Transl Med
Main Authors: McDonald, Chloe R., Cahill, Lindsay S., Gamble, Joel L., Elphinstone, Robyn, Gazdzinski, Lisa M., Zhong, Kathleen J. Y., Philson, Adrienne C., Madanitsa, Mwayiwawo, Kalilani-Phiri, Linda, Mwapasa, Victor, ter Kuile, Feiko O., Sled, John G., Conroy, Andrea L., Kain, Kevin C.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2018
Fag:
Malaria
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510298/
https://ncbi.nlm.nih.gov/pubmed/29514999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aan6007
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