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Increasing the precision of gene editing in vitro, ex vivo, and in vivo

New gene editing tools like CRISPR-Cas9 enable precision genome engineering within cell lines, primary cells, and model organisms, with some formulations now entering the clinic. “Precision” applies to various aspects of gene editing, and can be tailored for each application. Here we review recent a...

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Detalles Bibliográficos
Publicado en:Curr Opin Biomed Eng
Main Authors: Mueller, Katherine, Carlson-Stevermer, Jared, Saha, Krishanu
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510258/
https://ncbi.nlm.nih.gov/pubmed/31086832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cobme.2018.08.006
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