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Neonatal anesthesia impairs Synapsin 1 and Synaptotagmin 1, two key regulators of synaptic vesicle docking and fusion

Early exposure to anesthetics may interfere with synaptic development and lead to cognitive deficits. We previously demonstrated a decrease in vesicles docked at and within 100 nm from the presynaptic membrane in hippocampal nerve terminals of neonatal rats after anesthesia. Hence, we designed this...

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Detalhes bibliográficos
Publicado no:Neuroreport
Main Authors: Atluri, Navya, Ferrarese, Bianca, Osuru, Hari Prasad, Sica, Ryan, Keller, Caroline, Zuo, Zhiyi, Lunardi, Nadia
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510243/
https://ncbi.nlm.nih.gov/pubmed/30964765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000001235
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