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Understanding Ligand Binding to G-Protein Coupled Receptors Using Multiscale Simulations
Human G-protein coupled receptors (GPCRs) convey a wide variety of extracellular signals inside the cell and they are one of the main targets for pharmaceutical intervention. Rational drug design requires structural information on these receptors; however, the number of experimental structures is sc...
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| Izdano u: | Front Mol Biosci |
|---|---|
| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6510167/ https://ncbi.nlm.nih.gov/pubmed/31131282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00029 |
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