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Bortezomib and metformin opposingly regulate the expression of hypoxia-inducible factor alpha and the consequent development of chemotherapy-induced painful peripheral neuropathy

Chemotherapy-induced painful peripheral neuropathy is a significant clinical problem that is associated with widely used chemotherapeutics. Unfortunately, the molecular mechanisms by which chemotherapy-induced painful peripheral neuropathy develops have remained elusive. The proteasome inhibitor, bo...

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Publicado en:Mol Pain
Main Authors: Ludman, Taylor, Melemedjian, Ohannes K
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509977/
https://ncbi.nlm.nih.gov/pubmed/31041875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806919850043
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