Ectromelia virus suppresses expression of cathepsins and cystatins in conventional dendritic cells to efficiently execute the replication process

BACKGROUND: Cathepsins are a group of endosomal proteases present in many cells including dendritic cells (DCs). The activity of cathepsins is regulated by their endogenous inhibitors – cystatins. Cathepsins are crucial to antigen processing during viral and bacterial infections, and as such are a p...

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Vydáno v:BMC Microbiol
Hlavní autoři: Bossowska-Nowicka, Magdalena, Mielcarska, Matylda B., Romaniewicz, Marta, Kaczmarek, Monika M., Gregorczyk-Zboroch, Karolina P., Struzik, Justyna, Grodzik, Marta, Gieryńska, Małgorzata M., Toka, Felix N., Szulc-Dąbrowska, Lidia
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509786/
https://ncbi.nlm.nih.gov/pubmed/31077130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-019-1471-1
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