Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact

Recent evidence suggests that complex karyotype (CK) defined by the presence of ≥3 chromosomal aberrations (structural and/or numerical) identified by using chromosome-banding analysis (CBA) may be relevant for treatment decision-making in chronic lymphocytic leukemia (CLL). However, many challenges...

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Pubblicato in:Blood
Autori principali: Baliakas, Panagiotis, Jeromin, Sabine, Iskas, Michalis, Puiggros, Anna, Plevova, Karla, Nguyen-Khac, Florence, Davis, Zadie, Rigolin, Gian Matteo, Visentin, Andrea, Xochelli, Aliki, Delgado, Julio, Baran-Marszak, Fanny, Stalika, Evangelia, Abrisqueta, Pau, Durechova, Kristina, Papaioannou, George, Eclache, Virginie, Dimou, Maria, Iliakis, Theodoros, Collado, Rosa, Doubek, Michael, Calasanz, M. Jose, Ruiz-Xiville, Neus, Moreno, Carolina, Jarosova, Marie, Leeksma, Alexander C., Panayiotidis, Panayiotis, Podgornik, Helena, Cymbalista, Florence, Anagnostopoulos, Achilles, Trentin, Livio, Stavroyianni, Niki, Davi, Fred, Ghia, Paolo, Kater, Arnon P., Cuneo, Antonio, Pospisilova, Sarka, Espinet, Blanca, Athanasiadou, Anastasia, Oscier, David, Haferlach, Claudia, Stamatopoulos, Kostas
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2019
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509568/
https://ncbi.nlm.nih.gov/pubmed/30602617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-09-873083
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