A novel isoform of myosin 18A (Myo18Aγ) is an essential sarcomeric protein in mouse heart

Whereas myosin 18B (Myo18B) is known to be a critical sarcomeric protein, the function of myosin 18A (Myo18A) is unclear, although it has been implicated in cell motility and Golgi shape. Here, we show that homozygous deletion (homozygous tm1a, tm1b, or tm1d alleles) of Myo18a in mouse is embryonic...

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Published in:J Biol Chem
Main Authors: Horsthemke, Markus, Nutter, Lauryl M. J., Bachg, Anne C., Skryabin, Boris V., Honnert, Ulrike, Zobel, Thomas, Bogdan, Sven, Stoll, Monika, Seidl, Matthias D., Müller, Frank U., Ravens, Ursula, Unger, Andreas, Linke, Wolfgang A., van Gorp, Pim R. R., de Vries, Antoine A. F., Bähler, Martin, Hanley, Peter J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509511/
https://ncbi.nlm.nih.gov/pubmed/30737279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004560
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