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Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs

Expansion of transposable elements (TEs) coincides with evolutionary shifts in gene expression. TEs frequently harbor binding sites for transcriptional regulators, thus enabling coordinated genome-wide activation of species- and context-specific gene expression programs, but such regulation must be...

詳細記述

保存先:
書誌詳細
出版年:Cell Stem Cell
主要な著者: Pontis, Julien, Planet, Evarist, Offner, Sandra, Turelli, Priscilla, Duc, Julien, Coudray, Alexandre, Theunissen, Thorold W., Jaenisch, Rudolf, Trono, Didier
フォーマット: Artigo
言語:Inglês
出版事項: Cell Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509360/
https://ncbi.nlm.nih.gov/pubmed/31006620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.03.012
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